Phytochemical Screening, Total Antioxidant Capacity, and Toxicity Test of Basil Leaf Extract (Ocimum x africanum Lour)

Limanan, David (2021) Phytochemical Screening, Total Antioxidant Capacity, and Toxicity Test of Basil Leaf Extract (Ocimum x africanum Lour). Atlantis Press.

Text Basil_Leaf_Extract_Ocimum_x_africanum_Lour.pdf Download (1MB)

Abstract

High pollutant levels have caused an increase in disease that correlated with Reactive Oxygen Species through a condition that is oxidative stress. Oxidative stress can be stabilized with antioxidants by stabilizing active and unstable radicals to become inactive and stable. Basil leaves (Ocimum x africanum Lour) are known to have antioxidant capacity. The aim of this study is to determine the phytochemical profiling and antioxidant capacity of basil leaves extract. This research was conducted with an in vitro experimental study design. Extraction of this research was carried out by maceration method using methanol as solvent. The tests were carried out in the form of phytochemical tests to determine the content of secondary metabolites and antioxidant capacity tests using the DPPH method. In phytochemical test of basil leaf extract, it was found positive for secondary metabolites of alkaloids, anthocyanins, cardio glycosides, coumarins, Flavonoid, glycosides, phenols, quinones, saponins, steroid, terpenoids and tannins and the antioxidant capacity test obtained IC50 of 174.04 μg/mL. In this study we found that basil leaves contain secondary metabolites and antioxidants capacity but not as much as vitamin C, even though basil leave antioxidant capacity not as much as vitamin C, basil leave have other compound like Linalool that have antimicrobial and antioxidant activity, beside vitamin C also can induce acid reflux, so it can be concluded that basil leaves have secondary metabolites and the antioxidant capacity.

Item Type:	Other
Subjects:	Turnitin
Divisions:	Fakultas Kedokteran > Kedokteran
Depositing User:	FK Perpus
Date Deposited:	19 Jan 2024 08:53
Last Modified:	19 Jan 2024 08:53
URI:	http://repository.untar.ac.id/id/eprint/42626

Actions (login required)

View Item